New nanomedicine approaches using gold–thioguanine nanoconjugates as metallo-ligands

Dithiolene complexes as metallo-ligands: a crown-ether approach

Paramagnetic dithiolene complexes as metallo-ligands: ether/thioether coordination.

The secondary coordination ability of a paramagnetic nickel dithiolene complex, bearing an ether coordinating function within a nine-membered flexible ring, has been demonstrated in its [NiCl(DMF)(2)](+) complex, through coordination by both ether and thioether functions, allowing for a ferromagnetic interaction between both paramagnetic entities.

Nanomedicine Approaches for Corneal Diseases

Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye repeatedly. This often results in poor efficacy and...

Fullerenols as a New Therapeutic Approach in Nanomedicine

Recently, much attention has been paid to the bioactive properties of water-soluble fullerene derivatives: fullerenols, with emphasis on their pro- and antioxidative properties. Due to their hydrophilic properties and the ability to scavenge free radicals, fullerenols may, in the future, provide a serious alternative to the currently used pharmacological methods in chemotherapy, treatment of ne...

Nanomedicine Approaches for Treatment of Menopausal Symptoms

To the Editor, Following medical advances and the consequent increase in life expectancy during the recent decades, more women reach menopause each year. Menopause with resultant estrogen deficiency can lead to troublesome vasomotor symptoms, necessitating hormone replacement therapy (HRT). Despite all efforts made by the scientific community, the number of currently available treatment options...